The ER has many complex proteins and so have a robust system for heat-shock protein assisted folding9/20/2023 A stressor is an agent that produces stress at any time by different ways. ![]() In this context, stress response may be considered a nonspecific response of the body to any demand. Moreover, moderate challenges, which are also caused by stress, results in profitable physiological adjustments. In this way, challenges generate a stress situation to the body and, depending on the severity, can cause harmful effects. Thus, intense or critical challenges to life require numerous and complex mechanisms to restore or to maintain the homeostasis. The homeostatic regulation of any physiological variable depends on cooperative mechanisms which are activated simultaneously or in succession. ![]() ![]() These modifications are inseparable from a satisfactory adjustment of the physiological processes of the whole body, where physiological systems tend to maintain relatively constant composition of the internal environment (milieu intérieur), despite the constant challenges that the body is submitted daily to, which is known as homeostatic control. The ability of the human organism to respond with rapid and appropriate modification during physiological challenges is an essential feature for its own survival.
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